Prilosec

Prilosec OTC (Omeprazole 20mg)

Prilosec·$25.99
Generic Worth ItSave 42%
70% confidence345 votes
Verified Apr 2026

Generic Alternative

Equate

Equate Omeprazole 20mg

Equate

Walmart

$14.98

241

Same Quality

69

Close Enough

35

Not Worth It

Quick Facts

Ingredients ComparedConfirmed

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70%

Same Quality

20%

Close Enough

10%

Not Worth It

Evidence (1)

Ingredients✓ Confirmedby adminApr 6, 2026

Equate Omeprazole 20mg Delayed-Release is FDA-approved with the same active ingredient, dose, and delayed-release enteric coating as Prilosec OTC. Generic omeprazole is widely stocked by hospitals and prescribed by gastroenterologists in lieu of brand-name Prilosec.

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