Tylenol

Tylenol Extra Strength 500mg

Tylenol·$13.99
Generic Worth ItSave 57%
70% confidence482 votes
Verified Mar 2026

Generic Alternative

Up & Up

Up & Up Acetaminophen 500mg

Up & Up

Target

$5.99

337

Same Quality

96

Close Enough

49

Not Worth It

Quick Facts

Ingredients ComparedConfirmed

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70%

Same Quality

20%

Close Enough

10%

Not Worth It

Evidence (1)

Ingredients✓ Confirmedby adminApr 6, 2026

Up & Up Acetaminophen 500mg contains the same active ingredient at the same dosage as Tylenol Extra Strength. Generic acetaminophen is FDA-approved. Manufactured by Perrigo. Pharmacists consistently recommend generics as equivalent to name-brand OTC pain relievers.

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